Identification and functional analysis of novel facial patterning genes in the duplicated beak chicken embryo.
Nimmagadda S, Buchtová M, Fu K, Geetha-Loganathan P, Hosseini-Farahabadi S, Trachtenberg AJ, Kuo WP, Vesela I, Richman JM.
Nimmagadda S, et al.
Dev Biol. 2015 Nov 15;407(2):275-88. doi: 10.1016/j.ydbio.2015.09.007. Epub 2015 Sep 16.
Dev Biol. 2015.
PMID: 26385749
Free article.
We tested the functional effects of PI15 overexpression with a retroviral misexpression strategy. PI15 virus induced a cleft beak analogous to human cleft lip. We next asked whether PI15 effects were mediated by changes in expression of major clefting genes and genes in th …
We tested the functional effects of PI15 overexpression with a retroviral misexpression strategy. PI15 virus induced a cleft beak ana …